Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis

AJ Walker, M Grainge, TE Bates, TR Card - Cancer Causes & Control, 2012 - Springer
survival in glioma patients (multivariate HR = 1.16, CI = 0.57–2.34). For colorectal cancer, we
found that post-diagnosis tricyclic … Once again, when 3 months post-diagnosis are used to …

Antitumoral effects of tricyclic antidepressants: Beyond neuropathic pain treatment

A Asensi-Cantó, MD López-Abellán… - Cancers, 2022 - mdpi.com
… of antidepressants on the overall survival of the studied cohort of lung cancer patients [129]. …
TCAs translated to improved survival in patients with colorectal cancer or glioma showed no …

Antidepressants and colorectal cancer: A population-based nested case-control study

HC Lee, WC Chiu, TN Wang, YT Liao, IC Chien… - Journal of Affective …, 2017 - Elsevier
… Selective serotonin reuptake inhibitors (adjusted OR=1.00, 95% CI=0.94–1.06), tricyclic
antidepressants, serotonin-norepinephrine reuptake inhibitors, and serotonin antagonist and …

[PDF][PDF] Anti-cancer actions in commonly used drugs: epidemiology led by laboratory science

AJ Walker - 2011 - researchgate.net
cancers studied were; tricyclic antidepressants and both incidence and survival in a number
of cancer types, particularly glioma; … thesis, investigating NSAID use and colorectal cancer

Impact of polypharmacy for chronic ailments in colon cancer patients: a review focused on drug repurposing

R Giampieri, L Cantini, E Giglio, A Bittoni, A Lanese… - Cancers, 2020 - mdpi.com
… prevention of both colorectal cancer and glioma. The same group of authors in a following
paper [73] assessed the survival of CRC patients who used TCAs post-diagnosis: the authors …

Depression and quality of life in patients with gliomas: a narrative review

Y Hu, F Deng, L Zhang, K Hu, S Liu, S Zhong… - Journal of Clinical …, 2022 - mdpi.com
… with shorter survival in patients with gliomas, and patients with gliomas with … antidepressant
use on the risk of glioma [85,86]. Tricyclic antidepressants (TCAs) reduce the risk of glioma

[PDF][PDF] Effect of treating depressive disorders on mortality of cancer patients

C Sherrill, M Smith, C Mascoe, E Bigus, D Abbitt - Cureus, 2017 - cureus.com
tricyclic antidepressant (TCA) use on the survival outcomes in patients with either glioma or
colorectal cancer… For colorectal patients, post-diagnosis TCA exposure was associated with a …

Review of pharmacological treatment of depression in patients with primary brain tumour and proposal of modification in management strategy

OK Onyia, CU Onyia - Clinical Neurology and Neurosurgery, 2022 - Elsevier
… worsen overall survival and prognosis in patients with brain … inhibitors (SSRIs), the tricyclic
antidepressants (TCA) and the … of using TCAs for patients with glioma or colorectal cancer. …

Mitochondrial dysfunction in gliomas

CD Katsetos, H Anni, P Dráber - Seminars in pediatric neurology, 2013 - Elsevier
… both in the context of apoptosis and cell survival. In human … use of tricyclic antidepressants
in the treatment of glioma has … , thus inducing cell death in HM7 colon cancer cells. In addition, …

[HTML][HTML] A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the …

RE Kast, JA Boockvar, A Brüning, F Cappello… - Oncotarget, 2013 - ncbi.nlm.nih.gov
glioma patients showed a non-significant longer survival [“… those treated post-diagnosis with
tricyclic antidepressants [208]… (longer survival if treated with a tricyclic antidepressant) would …